Gastric Inhibition of the Drinking Response
- 1 August 1955
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 182 (2) , 227-231
- https://doi.org/10.1152/ajplegacy.1955.182.2.227
Abstract
Intravenous injection of 20% NaCl in dogs augmented water drinking. This drinking response was significantly inhibited if the stomach was distended for 20-40 minutes with water or a balloon in the stomach. Water into the rectum 30-40 minutes preceding salt administration moderately depressed drinking. Gastric distention failed to inhibit drinking if maintained for only 5 minutes prior to salt administration or if cocaine was applied to the gastric mucosa. Drinking response was delayed for 1 hour if the stomach was distended for 40 minutes and then deflated at the time of salt administration.Keywords
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