Dengue: a continuing global threat
Top Cited Papers
- 1 December 2010
- journal article
- review article
- Published by Springer Nature in Nature Reviews Microbiology
- Vol. 8 (S12) , S7-S16
- https://doi.org/10.1038/nrmicro2460
Abstract
Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases. Each year, there are ∼50 million dengue infections and ∼500,000 individuals are hospitalized with dengue haemorrhagic fever, mainly in Southeast Asia, the Pacific and the Americas. Illness is produced by any of the four dengue virus serotypes. A global strategy aimed at increasing the capacity for surveillance and outbreak response, changing behaviours and reducing the disease burden using integrated vector management in conjunction with early and accurate diagnosis has been advocated. Antiviral drugs and vaccines that are currently under development could also make an important contribution to dengue control in the future.Keywords
This publication has 141 references indexed in Scilit:
- The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing ActivityCell Host & Microbe, 2010
- Cross-Reacting Antibodies Enhance Dengue Virus Infection in HumansScience, 2010
- Prospective Study To Determine Accuracy of Rapid Serological Assays for Diagnosis of Acute Dengue Virus Infection in LaosClinical and Vaccine Immunology, 2007
- Monoclonal antibody-mediated enhancement of dengue virus infectionin vitroandin vivoand strategies for preventionProceedings of the National Academy of Sciences, 2007
- What do community-based dengue control programmes achieve? A systematic review of published evaluationsTransactions of the Royal Society of Tropical Medicine and Hygiene, 2007
- Altered Enzyme-Linked Immunosorbent Assay Immunoglobulin M (IgM)/IgG Optical Density Ratios Can Correctly Classify All Primary or Secondary Dengue Virus Infections 1 Day after the Onset of Symptoms, when All of the Viruses Can Be IsolatedClinical and Vaccine Immunology, 2006
- Development of Real-Time Reverse Transcriptase PCR Assays To Detect and Serotype Dengue VirusesJournal of Clinical Microbiology, 2006
- Localization of Dengue Virus in Naturally Infected Human Tissues, by Immunohistochemistry and In Situ HybridizationThe Journal of Infectious Diseases, 2004
- Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic feverNature Medicine, 2003
- Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease SeverityThe Journal of Infectious Diseases, 2000