Total Parenteral Nutrition and the Pancreas

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Abstract
To the Editor: The effect of total parenteral nutrition on pancreatic secretion is of paramount importance to those treating inflammatory diseases of the pancreas. Do the benefits of total parenteral nutrition for patients with pancreatitis derive from the effects of bowel rest or stem from the fact that it directly inhibits the pancreatic exocrine cell? A report in the Journal suggests that an indirect effect on pancreatic secretion is derived from the ability of total parenteral nutrition to place the bowel at rest and decrease tropic gastrointestinal hormones on a long-term basis.1 The authors observed that one month after total . . .