Synthesis of the L-Enantiomer of 4'-C-Ethynyl-2'-deoxycytidine
- 1 January 2001
- journal article
- Published by Oxford University Press (OUP) in Bioscience, Biotechnology, and Biochemistry
- Vol. 65 (8) , 1879-1882
- https://doi.org/10.1271/bbb.65.1879
Abstract
The L-enantiomer of 4'-C-ethynyl-2'-deoxycytidine (2) was synthesized, but did not show any activity against HIV-1 up to 100 microM.Keywords
This publication has 6 references indexed in Scilit:
- Syntheses of 4‘-C-Ethynyl-β-d-arabino- and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV ActivityJournal of Medicinal Chemistry, 2000
- Graphical abstractsTetrahedron Letters, 1995
- Synthesis of 4′-C-MethylnucleosidesBioscience, Biotechnology, and Biochemistry, 1993
- Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)The Journal of Organic Chemistry, 1992
- Protection of hydroxy groups by intramolecular oxidative formation of methoxybenzylidene acetals with DDQTetrahedron Letters, 1982
- Nucleoside syntheses, XXII1)Nucleoside synthesis with trimethylsilyl triflate and perchlorate as catalystsEuropean Journal of Inorganic Chemistry, 1981