Nuclear mutations in Saccharomyces cerevisiae which increase the spontaneous mutation frequency in mitochondrial DNA
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 170 (3) , 327-331
- https://doi.org/10.1007/bf00267066
Abstract
Fourteen mutants have been identified in which the frequency of spontaneous mutations in mitochondrial DNA is increased. As well as increasing the frequency of mutations to resistance to erythromycin, oligomycin and spiramycin, all the mutants also show changes in the frequency of spontaneous petite induction. None of the mutants has any effect on the frequency of spontaneous nuclear mutations. Nine of the mutants are in one complementation group and five are in another. The phenotype of both groups is caused by a single nuclear mutation.This publication has 26 references indexed in Scilit:
- Mitochondrial instability in a strain ofSaccharomyces cerevisiaeGenetics Research, 1978
- BACTERIAL MUTATOR GENES AND THE CONTROL OF SPONTANEOUS MUTATIONAnnual Review of Genetics, 1976
- Mitochondrial DNA synthesis in cell cycle mutants of saccharomyces cerevisiaeCell, 1975
- Molecular information in developmental geneticsCell, 1975
- Mitochondrial nucleic acids in the peptite colonie mutants: Deletions and repetitions of genesBiochimie, 1973
- Allelism tests of mutants affecting sensitivity to radiation in yeast and a proposed nomenclatureMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1971
- Genetic control of the cell division cycle in yeastJournal of Molecular Biology, 1971
- Recombination of mitochondrial drug-resistance factors in Saccharomyces, cerevisiaeBiochemical and Biophysical Research Communications, 1968
- Inhibition of mitochondrial synthesis in yeast by erythromycin: cytoplasmic and nuclear factors controlling resistanceGenetics Research, 1968
- Tetrazolium Overlay Technique for Population Studies of Respiration Deficiency in YeastScience, 1957