Thymosin-Induced Human Serum Factor Increasing Cyclic AMP
Open Access
- 1 September 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 119 (3) , 1106-1108
- https://doi.org/10.4049/jimmunol.119.3.1106
Abstract
Thymosin has virtually no in vitro effect on cyclic AMP levels in thymocytes and seems not to react with either the β-adrenergic receptor or with the putative human serum thymic factor (SF) receptor. However, when thymosin is injected into patients lacking SF activity, it induces the appearance of a serum factor which increases cellular cyclic AMP levels in thymocytes in vitro. This factor appears to act on a membrane site distinct from the β-adrenergic receptors.This publication has 0 references indexed in Scilit: