8-Carboxamidocyclazocine analogues: redefining the structure–activity relationships of 2,6-methano-3-benzazocines
- 12 March 2001
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 11 (5) , 623-626
- https://doi.org/10.1016/s0960-894x(01)00014-2
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- 3-Deoxyclocinnamox: The First High-Affinity, Nonpeptide μ-Opioid Antagonist Lacking a Phenolic Hydroxyl GroupJournal of Medicinal Chemistry, 2000
- 8-Aminocyclazocine analogues: synthesis and structure–activity relationshipsBioorganic & Medicinal Chemistry Letters, 2000
- (+)-cis-N-(para-, meta-, and ortho-substituted benzyl)-N-normetazocines: Synthesis and binding affinity at the [3H]-(+)-pentazocine-labeled (.sigma.1) site and quantitative structure-affinity relationship studiesJournal of Medicinal Chemistry, 1995
- Palladium-catalyzed synthesis of C3-substituted 3-deoxymorphines.Bioorganic & Medicinal Chemistry Letters, 1994
- 14.alpha.,14'.beta.-[Dithiobis[(2-oxo-2,1-ethanediyl)imino]]bis(7,8-dihydromorphinone) and 14.alpha.,14'.beta.-[Dithiobis[(2-oxo-2,1-ethanediyl)imino]]bis-7,8-dihydro-N-(cyclopropyl- methyl)normorphinone: Chemistry and Opioid Binding PropertiesJournal of Medicinal Chemistry, 1994
- An improved resolution of (±)‐cis‐N‐normetazocineJournal of Heterocyclic Chemistry, 1990
- Deoxymorphines: role of the phenolic hydroxyl in antinociception and opiate receptor interactionsJournal of Medicinal Chemistry, 1979
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973
- Analgesic 1-oxidized-2,6-methano-3-benzazocinesJournal of Medicinal Chemistry, 1972
- Benzomorphans. Optically Active and trans IsomersJournal of Medicinal Chemistry, 1967