ICI 74,917: A NEW ANTI‐ALLERGIC DRUG ADMINISTERED BY PRESSURISED AEROSOL
- 1 November 1975
- Vol. 30 (5) , 298-305
- https://doi.org/10.1111/j.1398-9995.1975.tb00206.x
Abstract
Ten patients with allergic rhinitis were challenged intranasally with allergen before, and half an hour, 2 hours and 4 hours after intranasal administration of placebo, disodium cromoglycate powder and an aerosol containing ICI 74,917, a new compound with anti-allergic action. ICI 74,917 had a maximum protective effect after half an hour, but was significantly better than placebo 2 hours after nasal use. The effect was significantly better than that of disodium cromoglycate powder. The results will encourage studies of ICI 74,917 in the treatment of allergic rhinitis.Keywords
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