Schizotypal personality and skin conductance orienting

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Abstract
This chapter focuses on the growing literature on the application of skin conductance orienting response (SCOR) to schizotypal personality, and attempts to place the findings of this field into a wider neuroscience context. The nature of SC orienting as a sensitive measure of information processing is outlined together with a very brief summary of key findings on SC orienting in schizophrenic patients and subjects at risk for schizophrenia. The SCOR has been viewed by many as a sensitive measure of information processing, reflecting the extent to which the subject pays attention to and cognitively processes the orienting stimulus. It is hypothesized that positive symptom schizotypals may be characterized by SC orienting deficits that reflect a lack of inhibition and working memory deficits underpinned by prefrontal dysfunction; and hyporesponsivity may be specific to schizotypals who are also antisocial.

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