The effects of water-soluble solutes on the phase transitions of phospholipids.
- 1 March 1984
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 81 (5) , 1398-1400
- https://doi.org/10.1073/pnas.81.5.1398
Abstract
A previous treatment [Sturtevant, J.M. (1982) Proc. Natl. Acad. Sci. USA 79, 3963-3967], based on ideal solution theory, of the influence of small molecules on the main phase transitions of phospholipid bilayers is extended to include the effect of water solubility of the added solute. This effect is manifested primarily in a sharpening of the phase transition, resulting from a buffering by the aqueous phase of the concentration of the solute in the lipid phases.Keywords
This publication has 2 references indexed in Scilit:
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- Thermodynamic constants for nonelectrolyte partition between dimyristoyl lecithin and waterThe Journal of Membrane Biology, 1974