The Microbiological Activity of an Oxygen Analog of Biotin

Abstract
The growth-stimulating activity of dl-hexa-hydro-2-Oxo-l-furo (3,4) imidazole-4-valeric acid (HIV) under conditions in which biotin was the limiting factor Was detd. for Lactobacillus arabinosus, L. casei and Saccharomyces cerevisiae. HIV was 50% as active with L. arabinosus and 40% with L. casei as natural d biotin. With S. cerevisiae the growth curve of HIV differed from biotin. The name dl-oxybiotin is proposed for HIV.

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