Carcinogen-Induced Sarcoma in the Primitive Primate, Tupaia glis

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Abstract
Sarcoma, metastatic in one instance, with a latent period of 6-7 months was induced in the primitive primate, T. glis by subcutaneous injection of 3,4-benzpyrene. Transplantation was successful in one instance with a pregnant animal. Growth in tissue culture was established from trypsinized fragments of the tumor. The fibroblastic cells demonstrated a lack of contact inhibition and contained cytoplasmic inclusion bodies.

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