Patterns of Infantile Hemangiomas: New Clues to Hemangioma Pathogenesis and Embryonic Facial Development
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- 1 March 2006
- journal article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 117 (3) , 698-703
- https://doi.org/10.1542/peds.2005-1092
Abstract
OBJECTIVES. Large facial infantile hemangiomas have higher rates of complications than small localized hemangiomas, more often require treatment, and can be associated with neurological, ophthalmologic, and cardiac anomalies (PHACE syndrome). The anatomic patterns of these hemangiomas are often referred to as “segmental” despite a lack of precise anatomic definitions. Our study aims to define “segmental” hemangiomas based on clinically observed patterns. Our secondary goal is to relate the observed patterns to currently accepted developmental patterns to gain insight into hemangioma pathogenesis and craniofacial development.Keywords
This publication has 15 references indexed in Scilit:
- The Nonrandom Distribution of Facial HemangiomasArchives of Dermatology, 2003
- A zone of frontonasal ectoderm regulates patterning and growth in the faceDevelopment, 2003
- Hemangiomas of InfancyArchives of Dermatology, 2002
- Tissue Origins and Interactions in the Mammalian Skull VaultDevelopmental Biology, 2002
- Neuroectodermal origin of brain pericytes and vascular smooth muscle cellsJournal of Comparative Neurology, 2001
- The many faces of PHACE syndromeThe Journal of Pediatrics, 2001
- Pericytes: Cell Biology and PathologyCells Tissues Organs, 2001
- The lines of Blaschko on the head and neckJournal of the American Academy of Dermatology, 2001
- Origins and Assembly of Avian Embryonic Blood VesselsaAnnals of the New York Academy of Sciences, 1990
- The control of avian cephalic neural crest cytodifferentiationDevelopmental Biology, 1978