The Farnesyltransferase Inhibitor, FTI-2153, Blocks Bipolar Spindle Formation and Chromosome Alignment and Causes Prometaphase Accumulation during Mitosis of Human Lung Cancer Cells

This publication has 26 references indexed in Scilit:

• The Phosphoinositide 3-OH Kinase/AKT2 Pathway as a Critical Target for Farnesyltransferase Inhibitor-Induced Apoptosis
  Molecular and Cellular Biology, 2000
• Increasing complexity of Ras signaling
  Oncogene, 1998
• Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts
  Oncogene, 1998
• Direct Demonstration of Geranylgeranylation and Farnesylation of Ki-Ras in Vivo
  Journal of Biological Chemistry, 1997
• K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors
  Journal of Biological Chemistry, 1997
• THE POTENTIAL OF FARNESYLTRANSFERASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS
  Annual Review of Pharmacology and Toxicology, 1997
• Inhibition of ras prenylation: A novel approach to cancer chemotherapy
  Pharmacology & Therapeutics, 1997
• PROTEIN PRENYLATION: Molecular Mechanisms and Functional Consequences
  Annual Review of Biochemistry, 1996
• How receptors turn Ras on
  Nature, 1993
• ras GENES
  Annual Review of Biochemistry, 1987