Glucocorticoid action on protein synthesis and protein breakdown in isolated skeletal muscles
- 15 September 1982
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 206 (3) , 641-645
- https://doi.org/10.1042/bj2060641
Abstract
The direct actions of glucocorticoid hormones on protein turnover were studied in isolated soleus muscles. These steroids were found to decrease the rates of both protein synthesis and protein breakdown within 3 h and 4 h respectively. Synthetic steroids (e.g. dexamethasone) were found to be more potent than naturally secreted hormones (e.g. cortisol) in inducing these changes, but only at concentrations in vitro less than 10nm.This publication has 23 references indexed in Scilit:
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