Primary Aldosteronism

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Abstract
Primary aldosteronism resulting from an adrenocortical adenoma (aldosteronoma), as described by Conn,1 is one of a few potentially curable forms of hypertension. Aldosteronoma is the most common cause of primary aldosteronism. Aldosteronomas are usually small (less than 2 cm in diameter), are benign, and have a golden yellow color on their cut surfaces (Figure 1), with different adrenal-cell types visible on microscopy. Idiopathic aldosteronism, which is associated with bilateral micronodular or macronodular adrenal hyperplasia, constitutes 20 to 30 percent of cases of primary aldosteronism,28 although it is considered by some to be a variant of essential hypertension.9 Unilateral adrenal . . .