Identification of HLA‐B*5136 in the Chinese population
- 23 February 2005
- journal article
- Published by Wiley in Tissue Antigens
- Vol. 65 (3) , 280-282
- https://doi.org/10.1111/j.1399-0039.2005.00373.x
Abstract
Abstract: We report here a new HLA‐B*5136 allele identified by sequence‐based typing in the Chinese population. The new B*5136 allele showed four nucleotides difference with B*5108 at exon 3, which are two point mutations at nucleotide positions 527 T→A and 583 C→T, and two substitutions at adjacent nucleotide positions 559 C→A and 560 T→C. This results in three amino acid changes from Val to Glu at codon 177, Leu to Thr at codon 187, and His to Tyr at codon 195.Keywords
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