Role of Macrophage Migration Inhibitory Factor in Hepatitis B Virus-Specific Cytotoxic-T-Lymphocyte-Induced Liver Injury

Open Access

1 March 2006

journal article
research article
Published by American Society for Microbiology in Clinical and Vaccine Immunology

Vol. 13 (3) , 415-419
https://doi.org/10.1128/cvi.13.3.415-419.2006

Abstract

Macrophage migration inhibitory factor (MIF) plays a pivotal role in the development of various inflammatory diseases. Here, we found that anti-mouse MIF antibody treatment reduced liver injury and inflammatory cell infiltration into the liver after injection of antigen-specific cytotoxic T lymphocytes into hepatitis B virus transgenic mice.

Keywords

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