CSF CALCIUM - CLINICAL CORRELATES IN AFFECTIVE-ILLNESS AND SCHIZOPHRENIA

1 January 1979

journal article
research article

Vol. 14 (1) , 37-51

Abstract

A positive correlation was found between Ca concentration and symptom severity in hospitalized depressed patients. CSF Ca levels tended to decrease as patients improved. In 4 rapidly cycling patients, CSF was higher during depression than during mania. Mean CSF Ca for the depressed patients as a group was not significantly different from neurological control or other psychiatric patients. Symptom remission from acute psychosis in schizophrenic patients was accompanied by a significant increase in CSF Ca concentration. Ca induced alterations in neuronal and physiological excitability were discussed.

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