An Enantioselective Synthesis of Cyclopentyl-L-Aspartic Acid Amenable to Large Scale
- 1 January 1997
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1997 (01) , 32-34
- https://doi.org/10.1055/s-1997-1518
Abstract
A new enantioselective synthesis of cyclopentyl-L-aspartic acid[(S)-αamino-1-(carboxy)cyclopentaneacetic acid] (1) and its N-Boc derivative 2 has been developed. This synthesis is amenable to kilogram scale preparation and avoids low temperature reactions and column chromatography.Keywords
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