Oral Solid Controlled Release Dosage Forms: Role of GI-Mechanical Destructive Forces and Colonic Release in Drug Absorption Under Fasted and Fed Conditions in Humans
- 1 January 1995
- journal article
- clinical trial
- Published by Springer Nature in Pharmaceutical Research
- Vol. 12 (7) , 1049-1054
- https://doi.org/10.1023/a:1016270701021
Abstract
Purpose. This study was undertaken to examine the effects of mechanical destructive forces on drug release from controlled release (CR) dosage forms in vitro and in vivoand their colonic release,...Keywords
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