Further Experiments with Cataract in Albino Rats Resulting from the Withdrawal of Vitamin G (B2) from the Diet

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Abstract
Cataracts have developed in nearly 100 per cent of the albino rats given diets freed of vitamin G (B2). Cataracts also developed in all the animals given a diet containing 25 per cent whole wheat and therefore containing a limited quantity of vitamin G. With this latter diet, however, the cataracts appeared at a later date, and the time of their appearance can be correlated with the greater growth and longer survival of this group of animals. It thus appears that in the diets used the growth-limiting and cataract-preventive factors are identical, or else these diets are similarly deficient in both. Cataract is suggested as a better criterion of vitamin G deficiency than dermatitis, as its appearance is more consistent and unmistakable, and also as its development is not influenced by external irritations and bacterial invasion which are undoubtedly contributing factors in the development of dermatitis.