Catalytic Asymmetric Synthesis of Esters from Ketenes
- 5 April 2005
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 127 (17) , 6176-6177
- https://doi.org/10.1021/ja0506152
Abstract
By building on elementary principles of Brønsted acid−base chemistry, a nucleophile-catalyzed method for the asymmetric synthesis of esters from ketenes has been transformed into a much more versatile and effective Brønsted acid-catalyzed process. The product aryl esters can be converted into useful derivatives, such as enantioenriched alcohols and carboxylic acids.Keywords
This publication has 3 references indexed in Scilit:
- Enantioselective Addition of Alcohols to Ketenes Catalyzed by a Planar-Chiral Azaferrocene: Catalytic Asymmetric Synthesis of Arylpropionic AcidsJournal of the American Chemical Society, 1999
- Effects of hydrogen bonding on the low-lying electronic states of a model polyene aldehydeJournal of the American Chemical Society, 1990
- 1,2-Dithiete is more stable than 1,2-dithioglyoxal as evidenced by a combined experimental and theoretical IR spectroscopic approachJournal of the American Chemical Society, 1989