Encapsulated islet cells: the role of direct and indirect presentation and the relevance to xenotransplantation and autoimmune recurrence
Open Access
- 1 January 1997
- journal article
- review article
- Published by Oxford University Press (OUP) in British Medical Bulletin
- Vol. 53 (4) , 777-788
- https://doi.org/10.1093/oxfordjournals.bmb.a011647
Abstract
Immuno-isolation of islet tissue for the purpose of curing diabetes without immunosuppression is an attractive concept that has been extensively investigated over the last 20 years. Rather than give a detailed review of the past and present history of the immuno-isolation or encapsulation approach for itself transplantation, this paper will examine the concepts behind encapsulation, concentrating on the immune mechanisms involved.Keywords
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