Postoperative complications after induction chemoradiotherapy in patients with non-small-cell lung cancer
Open Access
- 1 June 2006
- journal article
- research article
- Published by Oxford University Press (OUP) in European Journal of Cardio-Thoracic Surgery
- Vol. 29 (6) , 896-901
- https://doi.org/10.1016/j.ejcts.2006.03.023
Abstract
Surgical resection is still the best curative therapy for non-small-cell lung cancer (NSCLC); however, surgery alone is not adequate for most cases, considering a 5-year survival rate of less than 15% in stage IIIA-N2 disease and approximately 50% in T2N0 disease [1]. The theoretical advantages of pre-operative induction therapy lie in a potential increase in the resectability rate and a lower rate of distant relapse owing to eradication of micrometastases, both of which may contribute to achieving long-term survival for these patients. After encouraging results of several clinical trials for patients in stage IIIA-N2 disease [2,3], the concept of induction therapy followed by surgical resection found general acceptance and is now being adopted in patients with earlier stages of the disease.Keywords
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