Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues
- 3 May 2004
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 14 (9) , 2335-2338
- https://doi.org/10.1016/j.bmcl.2004.01.102
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Chapter 13. Emerging microtubule stabilizing agents for cancer chemotherapyPublished by Elsevier ,2002
- Evolution of a Gram-Scale Synthesis of (+)-DiscodermolideJournal of the American Chemical Society, 2000
- The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells???preliminary comparisons to paclitaxelAnti-Cancer Drugs, 1998
- Total Synthesis of (−)-Discodermolide: An Application of a Chelation-Controlled Alkylation ReactionThe Journal of Organic Chemistry, 1997
- Syntheses of Discodermolides Useful for Investigating Microtubule Binding and StabilizationJournal of the American Chemical Society, 1996
- (+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrestChemistry & Biology, 1996
- Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol,Biochemistry, 1996
- Total Synthesis of (-)-DiscodermolideJournal of the American Chemical Society, 1995
- Total synthesis of the immunosuppressive agent (-)-discodermolideJournal of the American Chemical Society, 1993
- Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissolutaThe Journal of Organic Chemistry, 1990