Polymorphism of Red Cell S-Formylglutathione Hydrolase in a Finnish Population
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 34 (5) , 273-277
- https://doi.org/10.1159/000153479
Abstract
Red cell hemolysates from a Finnish population sample (n = 242) were fractionated by isoelectric focusing on polyacrylamide gel, and S-formylglutathione hydrolase (EC 3.1.2.12) was located by activity staining. Polymorphism, which is probably genetically determined, was found. The samples from most persons studied gave one major enzyme band, whereas for 6 persons three enzyme bands were found. The enzyme is a dimer, and the polymorphism observed appears to result from two alleles, FGH1 and FGH2 at an autosomal locus. The frequency found for FGH1 was 0.988.Keywords
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