Clinical Pharmacokinetics of Toremifene
- 1 November 2000
- journal article
- review article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 39 (5) , 327-334
- https://doi.org/10.2165/00003088-200039050-00002
Abstract
Toremifene is a chlorinated triphenylethylene derivative of tamoxifen approved for use in the treatment of patients with metastatic breast cancer. Toremifene is well tolerated in patients, and common...Keywords
This publication has 26 references indexed in Scilit:
- Pharmacokinetic analysis of high-dose toremifene in combination with doxorubicinCancer Chemotherapy and Pharmacology, 1998
- ToremifeneDrugs, 1997
- Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomesBiochemical Pharmacology, 1994
- Targeting chemosensitizing doses of toremifene based on protein bindingCancer Chemotherapy and Pharmacology, 1993
- Phase I clinical and pharmacokinetics study of high-dose toremifene in postmenopausal patients with advanced breast cancerCancer Chemotherapy and Pharmacology, 1992
- A phase I study of toremifeneBreast Cancer Research and Treatment, 1990
- Pharmacokinetics of toremifeneJournal of Steroid Biochemistry, 1990
- Pharmacokinetics of toremifene and its metabolites in patients with advanced breast cancerCancer Chemotherapy and Pharmacology, 1990
- Biochemical and pharmacological effects of toremifene metabolitesCancer Chemotherapy and Pharmacology, 1990
- Biodistribution and Scintigraphy of11C-Toremifene in Rats Bearing DMBA-Induced Mammary CarcinomaBasic & Clinical Pharmacology & Toxicology, 1989