Elimination of Interfering Chromogens in the Zimmerman Reaction for Measuring 17-Ketosteroids

Abstract
A simple extraction technic is described for separating interfering chromogens from the 17-KS complex formed when the Zimmerman reaction is applied to urinary extracts. The procedure is performed immediately after the Zimmerman reaction is completed. It allows quantitation of the steroid present in a filter photometer at one wave length. Results compare favorably with those obtained after dilution of the Zimmerman complex with 70% aqueous ethanol and application of Allen's correction.

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