Steroids of pregnant mare's urine. 5. Identification of two androstane-3:16-diols. The structure of ‘uranolone’
- 1 April 1957
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 65 (4) , 663-668
- https://doi.org/10.1042/bj0650663
Abstract
The two neutral non-ketonic steroids of pregnant mare''s urine (compounds MN and MM of Brooks et al. 1952) are identified as the 5[alpha]-androstane-3[beta]:16[alpha]- (and -3[beta]:16[beta]-)diols. The constitution of "uranolone" (Marker et al. 1938b) is confirmed as 17[alpha][beta]-hydroxy-17[alpha]-methyl-5[alpha]-D-homoandrostan-3-one. Species differences in urinary steroids between the human female and the mare are discussed.Keywords
This publication has 12 references indexed in Scilit:
- IDENTIFICATION OF d-HOMOSTEROIDS IN EXTRACTS OF HUMAN URINEJournal of Biological Chemistry, 1956
- Potentiometric and other studies on preparations of cytochrome c from ox- and horse-heart muscleBiochemical Journal, 1956
- 16-SUBSTITUTED STEROIDS .13. ANDROSTAN-3-BETA,16-BETA-DIOL AND ANDROSTAN-3-BETA,16-ALPHA-DIOL1955
- The isolation of 16-epioestriol from the urine of pregnant womenBiochemical Journal, 1955
- The specificity of the dinitrobenzene reaction for ketosteroids.1954
- Steroids of pregnant mare's urine. 4. Fractionation of the neutral steroids. Examination of some non-ketonic fractionsBiochemical Journal, 1952
- Structure of UranediolNature, 1950
- The nature of pregnanediol-like glucuronideBiochemical Journal, 1950
- Colorimetric determination of substances containing the grouping —CH2.CO— in urine extracts as an indication of androgen contentBiochemical Journal, 1938
- A new saturated solid alcohol from the urine of pregnant maresBiochemical Journal, 1934