Pituitary Microadenoma and Hyperprolactinemia

Abstract
The recent development of precise and sensitive radioimmunoassay methods for the measurement of human prolactin has resulted in a large body of data concerning the regulation of this hormone in physiologic and pathologic states.1 The measurement of plasma prolactin has been of special interest in the diagnosis of pituitary and hypothalamic tumors.2 Approximately one third of patients with "nonfunctioning" chromophobe adenomas have been shown to have hyperprolactinemia.3 Since the advent of polytomographic radiologic investigation of the sella turcica has been a relatively recent technical development, the true frequency of prolactin secreting pituitary tumors has to be re-evaluated. In this regard, . . .

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