The evolution of the radiologic lead line.

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Abstract
Serial radiographs of Pb-poisoned children showed separation of Pb lines from the zone of provisional calcification within 4 wk at sites of rapid growth. Lead lines do not appear until blood Pb attains a concentration of 70-80 .mu.g/dl. They are not affected by treatment, but disappear spontaneously within 4 yr. While they remain in the diaphysis, they provide a marker for the time of onset of Pb toxicity and the subsequent rate of bone growth.