Pre-hospital opiate and aspirin administration in patients with suspected myocardial infarction

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Abstract
The benefit of immediate oral aspirin in the treatment of acute myocardial infarction is now established, having an equivalent impact to that of intravenous thrombolytic therapy in reducing early mortality.*RF 1-3* Though practical problems still exist with pre-hospital thrombolysis, aspirin can easily be given in this setting. Pain relief is a fundamental component and opiate analgesia is thought to be the most effective treatment. It is accepted that the route of administration should be intravenous rather than intramuscular, which can result in erratic absorption,4 haematoma formation, and a spurious increase in creatine kinase activity.5 The aim of this study was to assess the frequency with which aspirin was given acutely in patients suspected of acute …

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