Ruthenium-Catalyzed Propargylation of Aromatic Compounds with Propargylic Alcohols
- 14 September 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 124 (40) , 11846-11847
- https://doi.org/10.1021/ja027023t
Abstract
A novel ruthenium-catalyzed propargylation of aromatic compounds with propargylic alcohols has been found to afford the corresponding propargylated aromatic products in good yields with complete regioselectivity. The catalytic reaction provides a potential usefulness for practical application in organic synthesis, because the selective propargylation of aromatic compounds with an aromatic C−H bond cleavage is generally difficult.Keywords
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