HEAT LABILE OPSONINS TO PNEUMOCOCCUS
Open Access
- 1 December 1969
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 130 (6) , 1229-1241
- https://doi.org/10.1084/jem.130.6.1229
Abstract
When encapsulated type 25 pneumococci (Pn25) were opsonized with normal guinea pig serum, they consumed much more C3 than other complement (C) components. Fixation of C3 to the organisms was demonstrated by radio-labeling techniques, and its capsular localization was established by the use of monospecific anti-C3 antibody.Keywords
This publication has 26 references indexed in Scilit:
- Complement dependent immune phagocytosis: I. Requirements for C′1, C′4, C′2, C′3Experimental Cell Research, 1968
- THE ROLE OF COMPLEMENT IN RESISTANCE TO ENDOGENOUS AND EXOGENOUS INFECTION WITH A COMMON MOUSE PATHOGEN, CORYNEBACTERIUM KUTSCHERIThe Journal of Experimental Medicine, 1966
- STUDIES ON THE EFFECT OF EXPERIMENTAL NONKETOTIC DIABETES MELLITUS ON ANTIBACTERIAL DEFENSEThe Journal of Experimental Medicine, 1966
- Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serumImmunochemistry, 1966
- Studies on Phagocytosis of Bacteria by the Reticulo-Endothelial System in a Strain of Mice Lacking Hemolytic ComplementThe Journal of Immunology, 1964
- CORYNEBACTERIAL PSEUDOTUBERCULOSIS IN MICEThe Journal of Experimental Medicine, 1964
- VARIANCE ESTIMATION IN THE REED-MUENCH FIFTY PER CENT END-POINT DETERMINATION1American Journal of Epidemiology, 1964
- Studies on Heat-Labile Opsonin in Rabbit SerumThe Journal of Immunology, 1964
- ACTIVITY OF MOUSE COMPLEMENT1962
- STUDIES ON THE MECHANISM OF RECOVERY IN PNEUMOCOCCAL PNEUMONIAThe Journal of Experimental Medicine, 1941