Synthetic studies relevant to biosynthetic research on vitamin B12. Part 5. Synthesis of (RS)-ring-B imide
- 1 January 1987
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 8,p. 1679-1687
- https://doi.org/10.1039/p19870001679
Abstract
Future biosynthetic research on vitamin B12 depends on the synthesis of a family of isobacteriochlorin pigments. A key building block required for this work is 2-(2-methoxycarbonylethyl)-3-methoxycarbonylmethyl-3-methylsuccinimide, usually called the ring-B imide. A practical synthesis of the racemic form of this substance is described which can yield multigramme quantities of product.This publication has 2 references indexed in Scilit:
- Synthetic studies relevant to biosynthetic research on vitamin B12. Part 1. Syntheses of C-methylated chlorins based on 1-pyrrolines (3,4-dihydropyrroles)Journal of the Chemical Society, Perkin Transactions 1, 1984
- Natural Product Synthesis and Vitamin B 12Science, 1977