Pseudotumoral enterocolitis and massive eosinophilia.
Open Access
- 1 April 1983
- Vol. 24 (4) , 345-350
- https://doi.org/10.1136/gut.24.4.345
Abstract
We report a seven year history of a 23 year old woman born in the Antilles, with pseudotumoral enterocolitis and massive eosinophilia. In 1973 she developed a haemorrhagic colitis with massive peripheral eosinophilia of up to 60000/mm3. Medical treatment, mainly corticosteroids, failed to control the disease. The patient temporarily improved after colectomy and remained in remission for two years. In 1978 the disease recurred in the rectum and small intestine with formation of tumour-like granulomata and massive infiltration by eosinophils, unresponsive to corticosteroids. Intestinal blood and protein loss continued until death seven years after onset. In spite of exhaustive investigation, no parasites, allergens, or other aetiological agents could be found. As only the gut was infiltrated, the hypereosinophilic syndrome could be excluded. The enterocolitis here described does not correspond to an eosinophilic gastroenteritis, nor to other known inflammatory bowel diseases and to our knowledge has not been reported previously.Keywords
This publication has 26 references indexed in Scilit:
- Multifocal eosinophilic granuloma involving the common bile duct: Histologic and cholangiographic findingsGastroenterology, 1981
- The cardiovascular manifestations of the hypereosinophilic syndromeThe American Journal of Medicine, 1979
- The Spectrum of VasculitisAnnals of Internal Medicine, 1978
- Inflammatory fibroid polyp of the gastrointesthal tractHistopathology, 1978
- Eosinophilic gastroenteritisHistopathology, 1978
- THE HYPEREOSINOPHILIC SYNDROMEMedicine, 1975
- Localized Primary Extranodal Hodgkin's DiseaseAnnals of Internal Medicine, 1973
- EOSINOPHILIC GASTROENTERITISMedicine, 1970
- Primary Lymphoma of the Gastrointestinal TractAnnals of Surgery, 1969
- Idiopathic eosinophilic infiltration of the gastrointestinal tract, diffuse and circumscribed: A proposed classification and review of the literature, with two additional casesThe American Journal of Medicine, 1961