Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-β
Open Access
- 14 September 2006
- journal article
- Published by American Society of Hematology in Blood
- Vol. 109 (2) , 619-625
- https://doi.org/10.1182/blood-2006-06-027136
Abstract
Vaccinia virus (VV) has been used extensively as a vaccine vehicle in the clinical application for infectious diseases and cancer. Previous studies hKeywords
This publication has 47 references indexed in Scilit:
- Pathogen Recognition and Innate ImmunityCell, 2006
- Recognition of Cytosolic DNA Activates an IRF3-Dependent Innate Immune ResponseImmunity, 2006
- A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNANature Immunology, 2005
- IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionNature Immunology, 2005
- Toll-like receptor signallingNature Reviews Immunology, 2004
- Cross-priming of CD8+ T cells stimulated by virus-induced type I interferonNature Immunology, 2003
- Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling PathwayScience, 2003
- Two Roads Diverged: Interferon α/β– and Interleukin 12–mediated Pathways in Promoting T Cell Interferon γ Responses during Viral InfectionThe Journal of Experimental Medicine, 1999
- Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in VivoScience, 1996
- Functional Role of Type I and Type II Interferons in Antiviral DefenseScience, 1994