Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
Open Access
- 1 February 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (7) , 5685-5692
- https://doi.org/10.1074/jbc.m310803200
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- The clavulanic acid biosynthetic cluster of Streptomyces clavuligerus: genetic organization of the region upstream of the car gene The GenBank accession number for the 12162 bp sequence reported in this paper is AY034175.Microbiology, 2002
- ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activityEuropean Journal of Biochemistry, 2002
- Expansion of the Clavulanic Acid Gene Cluster: Identification and In Vivo Functional Analysis of Three New Genes Required for Biosynthesis of Clavulanic Acid by Streptomyces clavuligerusJournal of Bacteriology, 2000
- Biosynthesis and molecular genetics of clavulanic acid.Antonie van Leeuwenhoek, 1999
- The β-lactamase cycle: a tale of selective pressure and bacterial ingenuityNatural Product Reports, 1999
- Chemistry and biosynthesis of clavulanic acid and other clavamsNatural Product Reports, 1997
- Inhibition of TEM-2 β-Lactamase from Escherichia coli by Clavulanic Acid: Observation of Intermediates by Electrospray Ionization Mass Spectrometry,Biochemistry, 1996
- Clavulanic acid biosynthesis in Streptomyces clavuligerus: gene cloning and characterizationGene, 1995
- Penicillin resistance: the chemistry of .beta.-lactamase inhibitionAccounts of Chemical Research, 1985
- A new total synthesis of (±)-clavulanic acidTetrahedron Letters, 1979