A case of Yersinia pseudotuberculosis septicaemia is described in a patient with sickle-cell anaemia. This is believed to be the first reported instance of human infection with serotype V. The possibility that disordered iron metabolism might be the predisposing factor in this and other Y. pseudotuberculosis septicaemias is considered. We are grateful to Dr N. S. Mair for serotyping the strain, for antibody studies and for general interest, and to Dr A. G. Beckett under whom the patient was admitted.