The application of nuclear magnetic resonance to pharmacological problems

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Abstract
Nuclear magnetic resonance (nmr) was first discovered in the investigation of fundamental properties of matter but rapidly became an important method in chemical research because of the wealth of detail it is capable of giving about molecular structure. The application to purely biological problems is more recent, but a number of the basic techniques for studying biological systems are now established and more extensive use of the method is desirable. This survey is intended to accomplish two ends. Firstly to show that the basic principles of nmr spectroscopy are straightforward and easy to understand, and secondly to show the main ways in which this technique can be applied to problems of drug binding.