SERIAL GA-67-CITRATE IMAGING IN CHILDREN WITH NEOPLASTIC DISEASE - CONCISE COMMUNICATION

  • 1 January 1979
    • journal article
    • research article
    • Vol. 20  (3) , 210-214
Abstract
To investigate the role of Ga-67 imaging in children with neoplastic disease, 83 Ga-67 scans, obtained in 46 children with neoplastic disease, were retrospectively analyzed. The series included 19 children who had 2-5 serial Ga-67 scans while undergoing therapy over periods as long as 4 yr. Three patterns were identified in the children who had serial Ga-67 imaging: 12 children with tumors that were initially Ga-avid had normal scans after chemotherapy and/or radiotherapy: 4 children had persistently positive Ga-67 scans while being treated; and 3 children with Ga-avid tumors developed a normal scan after therapy, but later had a Ga-avid recurrence. All 12 children in the 1st group were alive and clinically disease-free after a mean followup time of 38 mo. Six of the 7 children with persistently Ga-avid tumors or Ga-avid recurrent tumors died during a mean followup time of 15.5 mo. Further investigation is warranted to determine whether the results of serial Ga-67 imaging have any prognostic significance in children with neoplastic disease.

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