Synthesis and Pharmacology of Ethylphenidate Enantiomers: The Human Transesterification Metabolite of Methylphenidate and Ethanol
- 25 March 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 48 (8) , 2876-2881
- https://doi.org/10.1021/jm0490989
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- New methylphenidate formulations for the treatment of attention-deficit/hyperactivity disorderExpert Opinion on Drug Delivery, 2005
- The role of dopamine D3 compared with D2 receptors in the control of locomotor activity: a combined behavioural and neurochemical analysis with novel, selective antagonists in ratsPsychopharmacology, 2004
- Stereoselective effects of methylphenidate on motor hyperactivity in juvenile rats induced by neonatal 6-hydroxydopamine lesioningPsychopharmacology, 2002
- Carboxylesterase-Mediated Transesterification of Meperidine (Demerol) and Methylphenidate (Ritalin) in the Presence of [2H6]Ethanol: Preliminary in Vitro Findings Using a Rat Liver PreparationJournal of Pharmaceutical Sciences, 1997
- Relationship between psychostimulant-induced "high" and dopamine transporter occupancy.Proceedings of the National Academy of Sciences, 1996
- Ethanol/cocaine interaction: Cocaine and cocaethylene plasma concentrations and their relationship to subjective and cardiovascular effectsLife Sciences, 1992
- Enantioselective behavioral effects of threo-methylphenidate in ratsPharmacology Biochemistry and Behavior, 1991
- [3H]Threo‐(±)‐Methylphenidate Binding to 3,4‐Dihydroxyphenylethylamine Uptake Sites in Corpus Striatum: Correlation with the Stimulant Properties of Ritalinic Acid EstersJournal of Neurochemistry, 1985
- Synthesis and pharmacology of hydroxylated metabolites of methyl phenidateJournal of Medicinal Chemistry, 1981
- Relative Hydrolytic Rates of Certain Alkyl (b) dl-α-(2-Piperidyl)-phenylacetatesJournal of Pharmaceutical Sciences, 1961