The Role of Antibodies and Serum Complement in the Interaction between Macrophages and Leptospires

Abstract
SUMMARY: Guinea-pig macrophages exerted bactericidal activity against both a virulent and a saprophytic strain of leptospira in the presence of the homologous IgG. Serum complement alone rendered the saprophytic strain susceptible to phagocytosis by the same macrophages.

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