THEIN VIVOINACTIVATION OF ESTRADIOL BY THE HUMAN LIVER

Abstract
Seven ovariectomized women with mesenteric estradiol implants showed little vaginal cornification, and a high incidence of menopausal symptoms up to 4 mos. postoperatively, while 4 similar women, with rectus muscle estradiol implants, showed a high level of vaginal cornification and no menopausal symptoms up to 7 mos. postoperatively.

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