p38 Kinase-dependent and -independent Inhibition of Protein Kinase C ζ and -α Regulates Nitric Oxide-induced Apoptosis and Dedifferentiation of Articular Chondrocytes
Open Access
- 1 August 2002
- journal article
- Published by Elsevier
- Vol. 277 (33) , 30375-30381
- https://doi.org/10.1074/jbc.m205193200
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Maintenance of Differentiated Phenotype of Articular Chondrocytes by Protein Kinase C and Extracellular Signal-regulated Protein KinaseJournal of Biological Chemistry, 2002
- Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C α activityOncogene, 2001
- Inhibition of Cell Cycle Progression by the Novel Cyclophilin Ligand Sanglifehrin A Is Mediated through the NFκB-dependent Activation of p53Published by Elsevier ,2001
- Epidermal Growth Factor Negatively Regulates Chondrogenesis of Mesenchymal Cells by Modulating the Protein Kinase C-α, Erk-1, and p38 MAPK Signaling PathwaysJournal of Biological Chemistry, 2000
- Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-mycJournal of Orthopaedic Science, 2000
- Protein kinase C-α overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawalOncogene, 1999
- Protein kinase Cα promotes apoptotic cell death in gastric cancer cells depending upon loss of anchorageOncogene, 1999
- Cloning and Characterization of the Murine PKC α Promoter: Identification of a Retinoic Acid Response ElementBiochemical and Biophysical Research Communications, 1999
- Ceramide Inactivates Cellular Protein Kinase CαJournal of Biological Chemistry, 1996
- PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in VivoJournal of Biological Chemistry, 1995