Oxidation of α-diazoketones derived fromL-amino acids and dipeptides using dimethyldioxirane. Synthesis and reactions of homochiral N-protected α-amino glyoxals
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 15,p. 1222-1223
- https://doi.org/10.1039/c39930001222
Abstract
Homochiral N-protected α-amino glyoxals are readily accessible by oxidation of α-diazoketones derived from natural amino acids and dipeptides using dimethyldioxirane in acetone; the glyoxals can be trapped efficiently in reactions such as Wittig olefination and condensation with amines and vicinal diamines.Keywords
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