Prevalence of antibody to delta antigen among HBV carriers in Japan
- 30 June 1987
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 22 (3) , 217-221
- https://doi.org/10.1002/jmv.1890220304
Abstract
Of 280 hepatitis B virus (HBV) carriers in Kure, Hiroshima Prefecture, Japan, 14 (5.0%) were seropositive for antibody to delta antigen (anti-HD by radioimmunoassay. HBV carriers with chronic liver disease had a greater frequency of seropositivity of anti-HD than asymptomatic HBV carriers (7% vs. 0%, P < 0.05). Among the various geographic regions of Kure, the east suburban area had a significantly higher prevalance of anti-HD when compared with all other regions combined (9.8% vs. 2.7%. P < 0.025). It is suggested that hepatitis delta virus (HDV) infection exists in Japan and HDV may be an etiologic agent of chronic liver disease.Keywords
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