Abstract
The ophthalmic literature of the last thirty years contains occasional references to a rare ocular disease characterized by the presence of fairly well-defined opacities situated in the central portion of the cornea. These opacities vary in size and contour and lie in the otherwise relatively clear tissue. The condition was not recognized as a distinct malady until Groenouw, in 1890,1and again in 1898,2made it the subject of clinical investigation and pathologic study. Since then a number of observers have dealt with the condition and a few have subjected the diseased tissue to histologic examination. Groenouw states that nodular opacity of the cornea begins with slight inflammatory signs, which are often so insignificant as to escape the notice of the patient. It attacks both eyes and is distinguished by the appearance of numerous, small, roundish or irregular, gray discrete opacities in the otherwise relatively clear corneal tissue. The larger

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