Arizona hinshawii Infections

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Abstract
Although disease caused by A. hinshawii [Salmonella arizonae] resembles the spectrum of clinical syndromes seen with Salmonella infections, little is known of their sensitivity to antimicrobials. Cases (3) illustrative of Arizona sepsis, localized infection, or both are presented. The literature is reviewed, and sensitivities to 12 antimicrobials for 32 human and animal isolates of A. hinshawii from various geographic areas are reported. With the exception of erythromycin and streptomycin, most strains were sensitive to many of the commonly used antibiotics. As with Salmonella infections, ampicillin or chloramphenicol appear to be the initial antimicrobial agents of choice for severe infections with A. hinshawii. Definitive antimicrobial therapy must be individualized on the basis of sensitivity testing and with regard to host factors. [Other antibiotics used were colistin, nalidixic acid, sulfadiazine, gentamicin, kanamycin, tetracycline, penicillin, sulfamethoxazole and trimethoprim, and cephalothin.].

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